Helen Benitez

LATINX HERITAGE MONTH

Meet Helen Benitez! Helen is a third-year Physiological Science major with a minor in Global Health. She is aspiring to obtain a medical career to expand the services available to minority groups in low-income areas and diversify the field to enhance the level of understanding between patients and the care team to improve the overall quality of care. Read more about what she’s currently researching, a bit about her background, and advice she has for other Latinx students!

1. What are your pronouns?

She/Her

2. What is your year and major?

I’m currently a junior (Class of 2026) majoring in Physiological Science with a minor in Global Health.

3. In one sentence, what are you currently researching?

I’m currently involved in cardiovascular research in Dr. Tzung Hsiai’s lab, specifically the development of cardiac atrioventricular valves!

4. What research experience did you have before joining a lab at UCLA?

None! As a first-generation college student, I had no idea what research was until coming to UCLA. I was first introduced to research through the UCLA Program for Excellence in Education and Research in the Sciences (PEERS) during my first year.

5. How did you first get involved in your current research project?

During my first year, I heard about an opportunity to conduct cardiology-related work in Dr. Tzung Hsiai’s cardiovascular bioengineering lab through a recent graduate in my club (Spanish in Healthcare). I was drawn by the lab’s focus on cardiology since it was a field within medicine that I was most interested in pursuing in the future. Upon speaking with graduate students, touring the lab, and discussing the current lab projects, I initially joined the lab as a student volunteer to work on a zebrafish project involving chemotherapy-induced cardiotoxicity associated with Doxorubicin (Dox). I recently transitioned my focus to work on our cardiac valve development project earlier this year.

6. How would you describe your research experience at UCLA?

Challenging, Exciting, Insightful/Invaluable. Getting involved with research at UCLA has provided me with an amazing opportunity for growth as an individual and scientist. Throughout my undergraduate career, I gradually gained confidence in my abilities and sought to become more involved in research: first as a student volunteer as a freshman, to now, working as a MARC trainee in my lab. It challenged me to think critically, embrace flexibility, and give myself grace, not only when learning new concepts or lab techniques, but also when dealing with personal struggles such as imposter syndrome. Previously, my scope of knowledge about STEM careers was limited since I had no family members or relatives who worked in such fields/areas. My research experience served as an avenue for exposure to science careers which greatly helped me consolidate my future career choice. The mentorship I have received from lab members and my PI has been invaluable to my growth as a scholar. The insights they have shared about their academic and personal journeys have broadened my scope of understanding of graduate/professional school and have begun to minimize the disadvantages I experience as a first-generation college student.

7. Can you share a bit about how your experiences growing up and your cultural background has influenced your decisions on your academic and career journey?

Growing up in an immigrant low-income household, I experienced many challenges due to my disadvantaged background and learned to be self-reliant at a young age. As the second oldest of 5, I desired to be a role model for my younger siblings and aspired to pursue higher education – an opportunity my parents never had – to advocate for the needs of my Latino community. Having experienced first-hand many health disparities due to my background, I aspire to obtain a medical career to expand the services available to minority groups in low-income areas and diversify the field to enhance the level of understanding between patients and the care team to improve the overall quality of care. In particular, I am interested in gaining exposure to the field of cardiology as understanding the functionality of the heart is critical in developing effective CVD treatments. Such advancements in medicine are significant since cardiovascular diseases disproportionately affect the Latinx community. As a Latina, I want to get involved in such areas of research to contribute towards discoveries in medicine that will empower Latinos and other people of color by addressing and reducing health illnesses that reduce their quality of life and ability to uplift themselves. The lack of Latinos/Hispanics in professional fields such as medicine and academia/science continues to ignite my passion for empowering my Latino community by being a role model to demonstrate that we can attain success through resilience and hard work.

8. Do you have any advice that you would give to Latinx students who are thinking about pursuing STEM or getting involved in research?

  • Don’t let imposter syndrome prevent you from even applying to desirable opportunities! There’s no harm in applying, so go for it!
  • Learn to advocate for yourself and build a supportive community that will encourage your research endeavors! I understand that it can be extremely daunting and discouraging to be the only Latino/Hispanic in the room, but remember, you have a seat at the table!
  • If you’re struggling with finding a research opportunity, talk to your peers and see how they got involved with their labs!

9. Please list any URC/departmental programs/clubs you are involved in.

  • Research related:
    • UCLA Program for Excellence in Education and Research in the Sciences (PEERS)
    • UCLA CARE Fellows
    • Maximizing Access to Research Careers (MARC) U*STAR Program
  • Non-research related:
    • PULSE UCLA (Pre-medical Undergraduate Learning through Shadowing Experience)
    • UCLA Spanish in Healthcare

Isabel Rosales

LATINX HERITAGE MONTH

Meet Isabel Rosales! Isabel is a third-year Biochemistry major, with an aspiring minor in Chicana/o Studies. She is currently doing research with the Diaconescu Group, exploring the reactivity of a metal-center catalyst to polymerize novel epoxide monomers. Read more about Isabel’s research-packed background and how her cultural background has influenced her current academic and career goals.

1. What are your pronouns?

She/Her

2. What is your year and major?

Third Year and Biochemistry Major, with an aspiring minor in Chicana/o Studies

3. In one sentence, what are you currently researching?

I am currently exploring the reactivity of a metal-center catalyst to polymerize
novel epoxide monomers.

4. What research experience did you have before joining a lab at UCLA?

Before joining the Diaconescu Group, my research experience consisted of my participation in the Biomedical Sciences Enrichment Program (BISEP) in the summer of 2023. In this program I learned about common experiments and techniques used in molecular biology laboratories.

5. How did you first get involved in your current research project?

I was looking to join a research laboratory that focused on chemistry and I saw that my Program for Excellence in Education and Research in the Sciences (PEERS) class page posted that the Diaconescu Group was looking for new undergraduates. As such, I began to read about their research concerning the use of redox-switchable catalysis to synthesize biodegradable multi-block copolymers. I was really intrigued by the process and the fact the synthesized polymers would be biodegradable. So, I sent an email to Dr. Diaconescu and she paired me up with my graduate student mentor, Shiyun Lin.

6. How would you describe your research experience at UCLA?

My research experience at UCLA could not have happened without the help of PEERS. They have helped me become less anxious about participating in research and seeing students like me, latina and first-generation students, in research. I find research highly rewarding as I am always learning and improving my skills in the laboratory. I get to apply the topics I learn in lecture to my research skills and vice versa. Being in research has only strengthened my interest in a career in the STEM field.

7. What are your future career goals?

Following the completion of my bachelor’s degree, I want to attend graduate school to study chemistry. Currently, I would like to research either materials chemistry or biochemical pharmacology. Post-graduate school I hope to either work for industry or for the government.

8. Can you share a bit about how your experiences growing up and your cultural background has influenced your decisions on your academic and career journey?

Growing up, my parents always emphasized to me that education and hard work were the most important things. Despite not having gone to college, my parents are the smartest people I know and I strive to be like them. In high school, I discovered my love for chemistry and decided I wanted to pursue that in university. My dream school has always been UCLA, as my aunt who did go to college attended here. As such, receiving my acceptance meant so much to me and my family. I strive to embody the two principles my parents instilled in me: learning and hard-work.

9. Do you have any advice that you would give to Latinx students who are thinking about pursuing STEM or getting involved in research?

Believe in yourself, you know more than you think you do. As long as you are interested in STEM, you are qualified to pursue it. You are never alone at UCLA, there are so many programs and the Undergraduate Research Center to help you get into research. They want to see you succeed and want to help you in your academic journey here at UCLA.

10. Please list any URC/departmental programs/clubs you are involved in.

I was involved with the Program for Excellence in Education and Research in the Sciences (PEERS), CARE Fellows, and Biomedical Sciences Enrichment Program (BISEP). I am currently apart of UC LEADS.

Cristian Ponce

LATINX HERITAGE MONTH

Meet Cristian Ponce, a third-year Microbiology, Immunology, and Molecular Genetics major, minoring in Biomedical Research. The URC-Sciences was able to learn a bit about Cristian’s current research in Dr. Anthony Covarrubias’ lab and how his cultural background ties into what is he working towards today. Read more about Cristian below:

1. What are your pronouns?

He/him/his

2. What is your year and major?

I am a rising third-year student majoring in Microbiology, Immunology, and Molecular Genetics and minoring in Biomedical Research.

3. In one sentence, what are you currently researching?

My current research aims at identifying genes associated with mitochondrial DNA production and how they can possibly serve as a novel target for treating age-related inflammation and diseases.

4. What research experience did you have before joining a lab at UCLA?

Absolutely none! One of my biggest insecurities when initially applying for lab positions was the fact that I had no understanding of practical research skills. But that’s the great thing about labs here at UCLA: they make sure to create a learning and collaborative environment that allows you to develop as a successful student researcher.

5. How did you first get involved in your current research project?

At first, it took a lot of reading to understand potential knowledge gaps I could address for my project. But then, after meetings with my mentors, I was guided to my first project, looking at a mitochondrial-bound enzyme necessary for DNA synthesis and how it can be targeted to attenuate markers of sterile inflammation.

6. How would you describe your research experience at UCLA?

It has been an amazing experience to participate in research at UCLA, especially in Dr. Anthony Covarrubias’s lab. The environment is welcoming, collaborative, and tight-knit. I’ve learned so much already and am super excited to see where my next two years at the lab will take me.

7. What are your future career goals?

Ultimately, my plan is to pursue a PhD and conduct research in aging and age-related diseases. I think it would be super neat to contribute to such a new and rapidly expanding field and support aging populations in increasing their quality of life.

8. Can you share a bit about how your experiences growing up and your cultural background has influenced your decisions on your academic and career journey?

Growing up in a Mexican household, right from a young age, I learned what it means to put in an honest day’s work and embrace resilience. This past summer was my first time constantly working on my project, and while there were plenty of ups and downs (mostly downs), I was motivated and driven towards my work. These were necessary and valuable experiences that demonstrated the difficulty but also the beauty behind biomedical research. So, going forward, I am even more motivated to conduct research and build a successful career in academia.

9. Do you have any advice that you would give to Latinx students who are thinking about pursing STEM or getting involved in research?

I would highly recommend that everyone reflect on their experiences and determine what fuels them to pursue STEM or become involved in research. Most of the time, research can be tedious, frustrating, and confusing. So, it takes a lot of motivation and resilience to become successful and create a lasting impression. But having that sense of drive, support, and vision can really make a difference.

10. Please list any URC/departmental programs/clubs you are involved in.

This past summer, I was fortunate to participate in the URC-Sciences Summer program under the direction of Dr. Jorge Avila. Going into this fall quarter, I will be participating in the Louis Stokes California Alliance for Minority Participation program funded by the NSF.

Angela Liang

STUDENT SPOTLIGHT

Meet Angela Liang! Angela is a fourth-year Physiological Science major and 2024 Amgen Scholar looking to “help advance scientific knowledge and hopefully use science to develop therapies and tools that enhance quality of life!” She credits the Amgen Scholars Program for allowing her to be “fully immersed in research as a full time researcher without the pressures of exams and classes” and feels that the program “does a very good job of developing each scholar as a scientist and equipping [students] with the skills to embark on the next part of [their] scientific journey.” She advises other students to “not be afraid to reach out to professors to ask about their research! In my experience, it has always been really fun. You never know until you ask, and the worst thing anyone can say is ‘no’.” Read more about Angela below.

1. How did you first get involved in your research project?
When I was first looking for a lab, I explored the faculty page of my departmental website, where there will often be a little blurb describing each faculty’s research interests or bio. I found a couple of professors whose research interests aligned with mine and explored their lab website and publications to get a sense of the specific projects in the lab and reached out!

2. How would you describe your research experience at UCLA?
My research experience has been incredibly rewarding and enriching. It is so exciting to be able to help advance scientific knowledge and work towards answering relevant questions. I have also met some of the best mentors and friends through research, and I am grateful that they have helped me become the person and scientist I am today.

3. What is your year and major?
I am a 4th year majoring in Physiological Science.

4. What is one piece of advice you have for other students thinking about getting involved in research?
One piece of advice is to not be afraid to reach out to professors to ask about their research! In my experience, it has always been really fun. You never know until you ask, and the worst thing anyone can say is “no” 🙂

5. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?
I have attended a couple of symposia where I had to present! Although presenting may seem intimidating, it is really fun to create a poster or presentation and discuss your project with others. To prepare to present, I recommend practicing with your research mentor, who can give valuable insights as someone familiar with the field. Because you will most likely be presenting to scientists who study different fields as well as those in your field, I also recommend practicing with mentors or friends whose research is not in your field, as they can give you a different perspective and advice on topics such as clarity. They can also let you know whether the terms and jargon that you are familiar with day to day are confusing, and you can edit your presentation based on their feedback.

6. Have you had your work published? Can you talk about what that process was like?
I have not had my work published.

7. What are your future career goals?
Since there is so much unknown, I would like to help advance scientific knowledge and hopefully use science to develop therapies and tools that enhance quality of life!

8. Please list any URC/departmental programs you are/were involved in. How has your experience been in AMGEN?
I was a part of the UCLA Amgen Scholars Program 2024 cohort and had a wonderful experience. It was rewarding to be fully immersed in research as a full time researcher
without the pressures of exams and classes. Additionally, the program does a very good job of developing each scholar as a scientist and equipping us with the skills to embark on the next part of our scientific journey. We had a wonderful writing instructor dedicated to helping us with our research papers and faculty mentors who guided us through the PhD or MD-PhD application process. We also had a symposium where we had the opportunity to meet Amgen Scholars from other universities in North America and learn about careers in science, which was eye-opening.

9. What was the impact of undergraduate research on your career path?
Before getting involved in research, I had little idea what a career in academia or industry would entail or that a career in research was possible. My research experiences have helped me realize my passion for research and allowed me to gain valuable insights into careers in science, which helped me solidify my goals.

10. What are your pronouns?
She/Her

Emily Silva

LATINX HERITAGE MONTH

Meet Emily Silva! Emily is a third year Neuroscience major with a minor in Musicology. She is currently conducting research in the Massaly Lab at UCLA that aims to understand pain-induced neuronal alterations and how they affect motivation-reward systems within the brain, paving the way for improvements in pain pharmacology. Read more about Emily’s research experience at UCLA, how her cultural background has influenced her academic and career journey, and advice she had for other Latinx student researchers.

1. What are your pronouns?

I use she/her/hers pronouns.

2. What is your year and major?

I am a third year Neuroscience major with a minor in Musicology.

3. In one sentence, what are you currently researching?

As an undergraduate SRP student in Massaly Lab at UCLA, I aid the team in research that aims to understand pain-induced neuronal alterations and how they affect motivation-reward systems within the brain, paving the way for improvements in pain pharmacology.

4. What research experience did you have before joining a lab at UCLA?

Before joining Massaly Lab, I took a two year AP Capstone course administered by the College Board in high school. This course required me to design an independent project. I investigated the effects of organic and non-GMO corn on the nutritional value of soil. After measuring pH, ammonia, potassium, and nitrogen over four weeks, I compiled a research paper that explained how GMOs are part of a solution to mass producing food when faced with climate change and soil erosion.

5. How did you first get involved in your current research project?

I first became involved in my research project after discussing with my mentors what I can do to help with a larger project that explores whether or not inhibiting a specific set of neurons causes effects in motivation. I communicated that my interests lie in aseptic surgery techniques and data analysis which led me to better understand the motivation-reward systems in the brain.

6. How would you describe your research experience at UCLA?

My research experience at UCLA is full of learning opportunities and is an overall challenge to remain proactive. My mentors provide me with much needed guidance in the wet lab environment and teach me the basic procedures I’d need to know as a student researcher from using proper protective equipment to operating a cryostat. My neuroscience courses reinforce my knowledge of the brain and shed light on the implications of scientific research in society, offering increasingly better alternatives to invasive procedures done on a number of health conditions.

7. What are your future career goals?

My goal is to continue developing my skills in research by learning how to expertly operate equipment, conduct experiments, and write out research papers. I’ll eventually apply these skills to graduate school after I complete my undergraduate years at UCLA.

8. Can you share a bit about how your experiences growing up and your cultural background has influenced your decisions on your academic and career journey?

I am an East LA native with a strong history of Hispanic culture and lived experiences supporting my development. As a first generation college student, I’ve learned how valuable it is to receive an education when many people who make up the pillars of my life rarely had the opportunity to think about pursuing a higher education. Instead, they thought about where to work or when the rent was due. Those before me worked under the sun so I can work with an air conditioner in the room. Neuroscience research as a career allows me to prioritize my interests and contribute to something larger than myself. With the aid of the scientific community, mentors, and peers, I am continually excited to help solve problems that impact people’s lives and represent my community in a field where Hispanics are largely underrepresented.

9. Do you have any advice that you would give to Hispanic students who are thinking about pursuing STEM or getting involved in research?

My advice to Hispanic students thinking about pursuing careers in STEM or exploring the sciences during their college career is to follow wherever your curiosity leads you with reasonable goals in mind. As a young student in college, you have little career experience and must learn, fail, and try again at any skills you’d like to develop inside or outside of research. Use this season of learning to your advantage. By consistently developing those skills, no matter how disconnected they may seem from the main goal, they will become more valuable to you in the future when you slowly see the life you worked for come into light.

10. Please list any URC/departmental programs/clubs you are involved in.

I am a former Care Extender volunteer and am currently involved in the PEERS, AAP, and LEAF programs at UCLA

Zahra Gill

Meet Zahra Gill! Zahra is a 4th year Molecular, Cell, and Developmental Biology major with a minor in Biomedical Research. Through her Biomedical Research minor prerequisite class (BR10H), Zahra was able to gain experience working with Drosophila, and credits this experience to her current placement at the Orsulic Laboratory. She was also involved in MCDB Departmental Honors, a year-long program where students conduct individual research under a faculty advisor, culminating into a full thesis. When asked about the impact of undergraduate research on her career path, Zahra says, “It completely changed my career path. I always had a passion for research but never believed I could pursue a career in research. My undergraduate research gave me the confidence that I can pursue my passion as a career.”

1. How did you first get involved in your research project?

I knew I wanted to gain research experience when I transferred to UCLA but knew how tough it can be especially for transfers to get a position in a lab. I signed up for a biomedical research minor prerequisite class (BR10H) and gained experience working with Drosophila. I loved this class and successfully applied to the biomedical research minor. I was able to get placed into my current lab, the Orsulic laboratory, with the help of the biomedical research minor. The faculty of the minor really helped me gauge my research interests and suggest labs that would be a good fit for me.

2. How would you describe your research experience at UCLA?

One word I would use to describe my research experience at UCLA is transformational. It is such a privilege to have access to mentors that are leaders in their field. I find even only as an undergraduate my perspective is valued and for me that has been quite empowering as a scientist.

3. What is your year and major?

4th year, Molecular, Cell, and Developmental Biology

4. What is one piece of advice you have for other students thinking about getting involved in research?

Getting involved in research can be a very intimidating process, and if you have even a sliver of interest in research try to pursue it one step at a time. The experience will be so valuable regardless of the outcome.

5. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

Yes, preparing was a bit stressful getting all my data together and creating a fluid story about my research project. However, once I was fully prepared, presenting was so much more fun that I expected. It was exciting answering questions about my research project and it even helped me think about my research in new ways.

6 .Have you had your work published? Can you talk about what that process was like?

Not yet 🙂

7. What are your future career goals?

I hope to attend graduate school after taking a gap year or two.

8. Please list any URC/departmental programs you are/were involved in.

MCDB departmental honors, Biomedical research minor

9. What was the impact of undergraduate research on your career path?

It completely changed my career path. I always had a passion for research but never believed I could pursue a career in research. My undergraduate research gave me the confidence that I can pursue my passion as a career.

Priscilla Yang

Meet Priscilla Yang! Priscilla is a recent UCLA graduate who received her B.S. in Bioengineering with a minor in Geography/Environmental Studies. She was involved in the Undergraduate Research Fellows Program (URFP) during the 2022-2023 academic year, a two-quarter program that supports UCLA students who are conducting a life science, physical science, or engineering research project with a UCLA faculty. Additionally, Priscilla was a 2023-2024 Internet Research Initiative Scholar (IRI), a program that supports research that addresses aspects of technology development, social trends or problems, ethics, and/or justice relating to the Internet. One piece of advice Priscilla has for undergraduate students thinking about getting involved in research is to “…prioritize good mentors — look for labs and professors who build uplifting learning environments and have a teaching style that works well for you! (I.e. Are you hoping to work 1-on-1 with a graduate student who is very hands-on? How often do you hope to talk with your professor about your research?).”

1. How did you first get involved in your research project?

I first got involved with my environmental engineering research after learning about my TA’s PhD research during class. I was excited about the impacts of such research, so I reached out, set up a meeting, and slowly got trained in the lab over the next couple of months!

2. How would you describe your research experience at UCLA?

I’ve had a very transformative and exploratory research experience at UCLA! I had the opportunity to join a variety of research projects: environmental engineering research at a formal UCLA lab regarding microbial technology for contaminant cleanup and wastewater treatment systems; co-leading a student-run research group as part of the Biomedical Engineering Society’s Research Team surrounding hydrogels for insulin delivery; and an individual creative research project through the Internet Research Initiative exploring music as a communication medium in healthcare. Through all of these, I found the fun in hands-on learning through experiments, critical thinking in experimental design and data analysis, and an overall passion for maneuvering between various scientific fields by using fundamental principles. Research at UCLA was also a key driver in my graduate school pursuits!

3. What is your year and major?

I just graduated in Spring 2024 with a B.S. in Bioengineering and a minor in Geography/Environmental Studies.

4. What is one piece of advice you have for other students thinking about getting involved in research?

My biggest piece of advice for students thinking about getting involved in research is to prioritize good mentors — look for labs and professors who build uplifting learning environments and have a teaching style that works well for you! (I.e. Are you hoping to work 1-on-1 with a graduate student who is very hands-on? How often do you hope to talk with your professor about your research?)

5. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

I had the opportunity to attend the BMES (Biomedical Engineering Society) Annual Meeting 2023 in Seattle during the fall! It was an enriching experience overall- my main reason for attendance was to present a poster about my research project within the Internet Research Initiative. Leading up to the conference, I worked to finalize my poster design, as well as draft, edit, and practice my pitch talk over and over. During the actual presentation, it was a lively atmosphere of students ranging from undergraduate to postdoctoral levels. Typically, the flow of events occurred with passerbys being interested in my poster title, me presenting my pitch talk, and them interacting and asking questions afterward. I even got to network on LinkedIn with fellow students as well!

Beyond presenting my poster, an unexpected yet useful experience I had at the conference was interacting with graduate school representatives at their booths. Since this was around the time where graduate school applications were being submitted, I was able to talk to current students at the programs I was looking at, along with admissions officers who provided application tips. Even better, a few schools offered application fee waivers just for your attendance! Beyond academic work, I was a volunteer for both the national BMES organization and the UCLA department of Bioengineering. Thus, I got to meet a variety of like-minded bioengineering students; moderate and learn about cutting-edge research panels; and share my personal experiences at UCLA bioengineering with prospective students! Overall, it was a worthwhile experience, and I’d encourage interested students to look into funding resources (Undergraduate Research Center fund, Academic Affairs Commission Travel Fund, etc) to help mitigate costs and make travel more accessible.

6. Have you had your work published? Can you talk about what that process was like?

I have not had my work published.

7. What are your future career goals?

I will be pursuing a master’s in Biomedical Engineering and a graduate minor in Entrepreneurship at Northwestern University this fall! Beyond that, I aspire to gain industry experience in the biotechnology space and potentially pursue a PhD and MBA in the future.

8. Please list any URC/departmental programs you are/were involved in.

Undergraduate Research Fellowship Program (URFP) – 2022-2023

Internet Research Initiative Scholar – 2023-2024

9. What was the impact of undergraduate research on your career path? 

Undergraduate research at UCLA played a pivotal role in my pursuit for graduate school in my career path. The creativity, critical thinking, collaborative, and communication skills that I developed through research have been instrumental in my career path, carrying me beyond the lab bench and into industry roles!

Austin Aguirre

Meet Austin Aguirre, a 4th year Microbiology, Immunology, and Molecular Genetic major and English minor. Austin is currently involved in the Maximizing Access to Research Careers (MARC) program, a two-year, NIH-funded, undergraduate honors program that seeks to increase the number of biomedical scientists from diverse backgrounds. He was also a part of the Program for Excellence in Education and Research in the Sciences (PEERS)– the program is committed to supporting academic excellence and professional development for students dedicated to careers in the life or physical sciences or mathematics. Austin’s current research revolves around urban ecology and the evolution of dark-eyed juncos through the investigation of antibiotic resistance in bacteria. Through the comparison of gut diversity and antibiotic resistance among rural and urban populations, the research explores how these juncos are affected by living in human-populated areas.

1. How did you first get involved in your research project?

I joined the Yeh lab during the winter quarter of my sophomore year. By that time, I had completed LS7A and LS7B, and was deeply fascinated by the various concepts in microbiology and ecology. As I started cold-emailing PIs, I knew I wanted to engage in research that bridged these two disciplines, and my current lab proved to be an ideal match. Our lab is dedicated to studying the urban ecology and evolution of birds, specifically dark-eyed juncos, and investigating antibiotic resistance in bacteria as well. I am currently involved in a project that aims to characterize the gut microbiota of juncos. The goal is to assess and compare the gut diversity and antibiotic resistance among rural and urban populations, exploring how these juncos are affected by living in human-populated areas.

2. How would you describe your research experience at UCLA?

My research experience at UCLA has been both rewarding and fulfilling. I feel extremely fortunate to have joined a supportive lab community, with mentors who have supported my future research endeavors. A special shoutout to my graduate student mentor, Wilmer, for helping me hone my scientific skills. The sense of community among UCLA researchers has been a highlight, and I’ve enjoyed discussions with various professors, teaching assistants, and fellow students about their research outside of class. I am also grateful to have found additional community and support through the NIH MARC program here at UCLA. Being a MARC scholar has significantly enhanced my research experience, providing profound opportunities, including assistance in attending research conferences and securing summer research positions.

3. What is one piece of advice you have for other students thinking about getting involved in research?

It might feel intimidating to join a lab, but at UCLA, there’s an immense number of resources and opportunities to help you get started. It’s crucial to actively seek them out. Being part of PEERS in my early college years was a big help for me. For a leg up, I’d suggest subscribing to the URC-Sciences newsletter to find new opportunities! Networking and staying curious are your best tools for finding your place in research.

4. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

I’ve presented my research three times at research conferences thanks to my participation in MARC. I’ve attended ABRCMS twice in addition to the Leadership Alliance’s National Symposium as a summer research intern at the University of Pennsylvania. Attending conferences can initially feel intimidating, but from my experience, it’s really a time to celebrate the progress you’ve made in research and have fun. In preparing conference presentations, I’ve found that a strong background is key. Make sure to clearly explain the background so that as

you present your results, you can keep linking them back to this context. This helps to ensure that your audience can easily follow and comprehend your research narrative.

5. Have you had your work published? Can you talk about what that process was like?

I have not had my work published yet, but I’m currently writing a manuscript for my project.

6. What are your future career goals?

My goal is to earn a PhD in microbiology, and I aspire to become a principal investigator in infectious diseases research. I am particularly interested in HIV research, a field I delved into this past summer at the University of Pennsylvania. I plan to apply to PhD programs soon. Meanwhile, I am thankful for the opportunity to extend my research journey post-college as a PREP Scholar at the Icahn School of Medicine at Mount Sinai, within their Graduate School of Biomedical Sciences.

Sophia Rueda

Meet Sophia Rueda, a 3rd year neuroscience major. Sophia is currently engaged in the Maximizing Access to Research Careers (MARC) program, a two-year, NIH-funded, undergraduate honors program that seeks to increase the number of biomedical scientists from diverse backgrounds that significantly impact health-related research. Prior to this, she was also a part of Program for Excellence in Education and Research in the Sciences (PEERS) and CARE Fellows–both programs that support students development of a strong foundation in the sciences and make teaching and/or research a part of their life’s work. Sophia is currently a part of the DeNardo Lab, where she completes research focused on investigating the brain-wide changes in circuit function following repetitive magnetic stimulation (rTMS), a promising and noninvasive depression treatment.

1. How did you first get involved in your research project?

Before arriving at UCLA, I knew that I was very passionate about the intersection between neuroscience and mental health. During freshman and sophomore year I was fortunate enough to be a part of the PEERS research program which helped me navigate the ins and outs of research at such a big campus. During this exploration, I sought out labs that resonated with my interests in neuroscience, ultimately discovering the DeNardo Lab during my sophomore year. Since then, I’ve been immersed in investigating brain-wide changes in circuit function following repetitive magnetic stimulation (rTMS), a noninvasive depression treatment.

2. How would you describe your research experience at UCLA?

My research experience at UCLA has been incredibly enriching and insightful. Under the guidance of mentors at the DeNardo Lab, I’ve evolved both as a scientist and as a critical thinker, gaining confidence in my research skills. The supportive and collaborative atmosphere within the lab community has been instrumental in my personal growth. I have been lucky to be part of a community where everyone is happy to share advice and creative ideas.

UCLA has provided me with invaluable opportunities such as the CARE Fellows program and the MARC Program. These programs have allowed me to hone my technical skills such as mock grant writing, thesis development, and creating research posters. These experiences have deepened my appreciation for the complexities of research and the dedication required to advance knowledge in the field. I am very excited to be able to continue embarking on independent projects at the Summer 2024 Undergraduate Research Internship at the University of Pennsylvania which I could not have done without all of my wonderful mentors at the MARC program.

3. What is one piece of advice you have for other students thinking about getting involved in research?

Entering the field of research can be daunting, and setbacks are inevitable. Experiments will not always go as planned and your questions may not always have clear answers. However, each obstacle is an opportunity for you to learn and grow. Approach every research endeavor with an open mind, passion, and perseverance. Embrace the unknown, as unexpected results often lead to new insights. Remember, mistakes and failures are integral parts of the journey and should never diminish your self-worth.

4. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

With the support of the MARC program, I had the privilege of attending the 2023 ABRCMS conference, where I showcased the research we have been conducting in the DeNardo Lab. Throughout last summer, I dedicated myself to developing a deep learning pipeline to analyze mouse brain slices post-rTMS treatment. With this brain wide activation data, we were able to propose a model of the effects of rTMS on circuit function. My preparation for the conference involved creating a poster with guidance from my research mentor, rehearsing my presentation, and answering questions from members of the lab, friends, and family. I wanted to ensure that I could communicate my ideas effectively even to those outside the field of neuroscience. Although a nerve-racking experience at first, I had the opportunity to discuss my research and future goals with brilliant researchers from all over the country. This conference definitely reinvigorated my passion for neuroscience and allowed me to grow as a scientist. I can’t wait to attend again next year!

5. Have you had your work published? Can you talk about what that process was like?

I contributed to a project currently undergoing the review process on the role of the retrospenial cortex in the emergence of persistent memories. Currently, I have also been working with my mentor on crafting the publication detailing our rTMS findings. Although writing a paper can be a lengthy process, it has allowed me to grasp the big picture and significance of our project. I have also learned the importance of communicating science in an engaging and meaningful way.

6. What are your future career goals?

My goals are to attend graduate school and pursue a PhD in either Neuroscience or Clinical Psychology where I will continue to explore my love for the brain and mental health. I hope to continue using creative research ideas and scientific tools to improve treatment protocols and outcomes for people around the world. Due to my passion for working with kids, I would also love to construct educational programs that mold young scientists. My dream would be to bring these tools and programs back to those in underserved communities in my home country, Colombia. I am dedicated to becoming a socially aware researcher who helps bridge the gap between academia and those in our community.

Jeff Qu

Meet Jeff Qu, a 4th year Biochemistry major and Structural Biology minor. Jeff is currently a member of the Integrated and Interdisciplinary Undergraduate Research Program (i2URP), a two-year academic development program that prepares juniors and seniors for graduate studies and careers in biomedical research by improving their comprehension of scientific literature and sharpening their presentation skills. He was also a part of the 2022-2023 Undergraduate Research Scholars Program (URSP) and 2021-2022 Undergraduate Research Fellows Program (URFP)–both programs that support students conducting a life science, physical science, or engineering research project with a UCLA faculty. We had the opportunity to interview Jeff about his research experience at UCLA.

1. How did you first get involved in your research project?

I was curious about the research in biochemistry and how we obtained the understanding of vital life processes in molecular details as I took some classes in chemistry and biology. Then I looked at the URC and departmental website on research opportunities, then I joined the lab by emailing my current PI Dr. Jose Rodriguez. It was in the pandemic, so I picked up a computational project that allowed me to learn coding from the very beginning and understand how to utilize computational tools to probe molecules in silico. After I was on campus, I continued to work on computations as well as getting trained on experimental techniques. Then I begun my independent research project on using machine learning to predict how prone is the proteins to misfold and turned themselves into pathological aggregates known as amyloids.

2. How would you describe your research experience at UCLA?

I will say I am really lucky to join the lab with a welcoming atmosphere in undergraduate research as everyone is willing to offer much great advice in research and college life. Not only does my PI encourage me to explore new opportunities and research topics but also my graduate student mentors Samantha Zink and Niko Vlahakis are always there to help me with research training, suggestions for college life, and navigating my career goals. Throughout my experience in the lab, I was exposed to various dimensions of research in structural biology from computational analysis on molecules to experimental structure elucidation, from physics in microscopes to biology in functional assemblies and all of them are conveyed by my awesome mentors who are willing to help me out from the scratch. Other help from the programs at URC is also a key factor to prepare me to become more acquainted with scientific research and all of those people contributed to my meaningful research experience.

3. What is one piece of advice you have for other students thinking about getting involved in research?

In my opinion, being active when thinking about research projects as well as communicating with others is really important to become a researcher. I feel like the shift of perspective from a student to a researcher is achieved through actively learning and asking questions to carry out research projects rather than simply conducting experiments. I gained many valuable insights from my peers and mentors when I had some questions about my research or recent publications. Most importantly, I became more excited about research as I gained more understanding about the project so active learning and engaging in conversations really encouraged me to explore more about the field.

4. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

I presented my work at the West Coast Structural Biology Workshop 2023, and it was a really nice experience. Before the presentation I was putting all my work together to a poster and I learned a lot about how to make the poster more compelling and readable from lab members. And we have to give a flash talk prior to the meeting so formatting all my research highlights to a 2-minute talk was also quite challenging. Anyways it is a really nice experience, my presentation was welcomed by many researchers from other universities, and I discussed and gained a lot of suggestions from other people and their research.

5. Have you had your work published? Can you talk about what that process was like?

We are now currently working on drafting the paper, so it is another experience to put everything together into a story. We also established a website for our tool to the research community and it is pretty fun to build it with my mentor.

6. What are your future career goals?

I am thinking about getting a PhD degree after undergraduate, and I am planning to stick around generally with biophysics and biochemistry. After obtaining my doctoral degree, I plan to continue doing professional research in academia or industry.