Soumya Ravichandran

Meet Soumya Ravichandran, a UCLA senior majoring in Psychobiology. Soumya was was able to present her research at the Obesity Society Obesity Week 2020 conference. Recently, she was also published as a first author in Scientific Reports for her paper titled, “Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals.”

Soumya has been conducting research as part of Dr. Arpana Gupta’s lab in the Division of Digestive Diseases in the UCLA Department of Medicine.

 

How did you first get involved in your research project?

While I had some exposure to research in high school, it was my interest in neuroscience that propelled me to join my current lab during my freshman year of college under my PI, Dr. Arpana Gupta. During my first few quarters in the lab, I spent my time learning the basics of neuroimaging modalities and performing literature reviews on the brain-gut axis. As I became more acclimated with the lab, my PI encouraged me to shadow another student who was researching sex differences in resting state connectivity in obese individuals. It was through this experience that I became fascinated with exploring the neural correlates of food addiction across males and females. With the help of my PI and research mentors, I decided to pursue this independent research project through the next year with the goal of finding sex-specific connectivity differences in individuals with food addiction that could clinically contribute to the variability seen in their response to diet interventions.

How would you describe your research experience at UCLA?

Extremely rewarding. Coming to college, I had no idea the extent of opportunities that undergraduates would be exposed to. With every step of the way in my project, my research mentors and fellow students have offered me such a strong support system by always offering new insights and constructive solutions to my research efforts. I am also extremely grateful to my PI for her constant encouragement, without which I would not have been able to experience such enriching opportunities such as presenting at a national conference or publishing a manuscript. In addition to deepening my own knowledge, being involved in research at UCLA has allowed me to grow as a writer, reader, and independent thinker; all skills that will carry with me onto future endeavors.

What is one piece of advice you have for other students thinking about getting involved in research?

Finding a lab that complements your research interests is incredibly important. Many students often jump into a lab for the sake of a resume boost or simply for the eagerness to get involved in a research project. However, rushing into a lab that you may not be fully interested in often leads to burnout or discouragement when faced with minor setbacks or difficulties. Taking the time to learn about the lab’s work and mentally checking if it is the right fit for you, prior to joining, can benefit you in the long run by making significant strides in your research much easier to achieve.

What are your future career goals?

I plan to attend medical school and pursue my goal of becoming a doctor after completing my undergraduate degree at UCLA. However, through this path, I plan to continue my research involvement and hopefully be able to translate the clinical implications of my research to create tangible improvements in patient care. Prior to my college, I had always thought of a career in medicine and one in research as two mutually exclusive paths. However, I now realize the interconnectedness of these two fields and the imperativeness of research efforts in order to improve the future of medicine with regards to targeted interventions, personalized medicine, and novel therapeutic techniques.

David Chung

Meet UCLA senior, David Chung, who is majoring in Applied Mathematics and minoring in Biomedical Research. David was selected to present at the 2021 Harvard National Collegiate Research Conference, the largest student-run conference in the nation. His poster was titled, “Chemogenetic modulation of parvalbumin-positive interneurons to rescue circuit defects in developing somatosensory cortex and tactile defensiveness in the Fragile X mouse.”

David currently conducts research in Dr. Carlos Portera-Cailliau’s lab in the Neurology department at David Geffen School of Medicine.

Read David’s interview with us below:

How did you first get involved in your research project?

Coming into UCLA, I had a number of interests, but I was especially fascinated with neuroscience. Wishing to learn more about this subject, I discovered that one of the most effective ways to learn was through direct exposure, and thus I sought an experience within research. Through the Biomedical Research Minor, I was introduced to Dr. Carlos Portera-Cailliau whose lab researches Fragile X Syndrome, an autism spectrum disorder. I was not only interested in the neuroscience behind autism disorders, but also drawn to this research due to my family history, as I have a cousin with autism. Because of this intersection of my interests, I joined the lab in 2019, where I continue to contribute to an ongoing project. My work specifically focuses on understanding the network level activity of neurons in a Fragile X mouse model, and how modulating specific groups of cells may produce cellular and behavioral changes.

How would you describe your research experience at UCLA?

My research experience at UCLA has been enriching and especially helpful in shaping my future career goals. I discovered a passion for research that I would have never known, had I not taken the first steps to become involved in it. It has taught me a number of technical skills, such as scientific writing, surgeries, and imaging techniques, and most importantly, how to think scientifically and logically. The ideas and concepts we may learn in biology or neuroscience classes become the necessary background material, as research helps me cultivate a more creative approach to solving real world problems. I often thought of what “the real world” may be, and I realized in my experiences in research, this is exactly that. As a future researcher, I will be able to develop ways to understand mysteries in science and tackle new questions that may arise every day. My experience in research at UCLA has been one of the most important factors in defining my future.

What is one piece of advice you have for other students thinking about getting involved in research?

The most important aspects of research are a curiosity of the world around you and the drive to answer questions. If you are truly interested in understanding a certain field or answering a certain question, I implore you to first read as much as you can about the topic, then find someone you can learn even more from. The internet is a wonderful place to start to understand the necessary background for a certain subject, and professors are also excellent resources for finding avenues into research. A genuine passion shows clearly, and with that I encourage you to reach out to researchers to ask to talk and learn more about the field you are interested in, and you may find yourself with a great research mentor.

What are your future career goals?

I wish to pursue a career as a physician-scientist. After graduation, I intend to gain more research experience in other fields of study with neuroscience. I then intend to apply to MD-PhD programs, where I hope to obtain a PhD in Neuroengineering or Computational Neuroscience. Eventually, I hope to specialize in Vascular Neurology or Movement disorders as a physician, and lead a lab at an academic institution. Currently, my new interests direct me to research Brain Computer Interfaces, and one day I hope to be able to see the applications of my research in the clinical setting.

Kelly Huang

Meet UCLA junior, Kelly Huang, who is majoring in Biology. Kelly recently had her abstract accepted and will be presenting at the California Society of Plastic Surgeons 2021 Symposium. Her abstract is titled, “Developing the Psychosocial Growth Chart: Prospective Longitudinal Psychosocial Functioning of Children with Craniofacial Anomalies.”

Kelly currently works in the lab of Dr. Justine Lee, at David Geffen School of Medicine, who specializes in Plastic Surgery and Pediatrics.

Kelly is also currently a part of the URC-Sciences’ Undergraduate Research Scholars Program (URSP).

How did you first get involved in your research project?
I was shadowing in the operating room during the summer after my freshman year when I serendipitously observed a surgeon repurpose abdominal tissue to perform a breast reconstruction for a woman who had a mastectomy due to breast cancer. I became fascinated with the potential of reconstructive surgery to transform someone’s quality of life and started looking for opportunities to learn more about the field. Fortunately, during my study abroad at Yonsei University in South Korea, I had the amazing opportunity to shadow a reconstructive surgeon at the Severance Hospital. After learning more about the specialty, I returned to UCLA and reached out to Dr. Justine Lee at the David Geffen School of Medicine to study the intersection between surgical care and psychosocial functioning. It has been a transformative experience working under Dr. Lee’s guidance alongside supportive and inspiring medical students to evaluate the longitudinal psychosocial development of children with craniofacial anomalies to improve their standard of care.

How would you describe your research experience at UCLA?
Conducting research at UCLA has been essential in shaping my understanding of science and medicine and my career aspirations. I’m always thinking of how lucky I am to have such opportunities to work with amazing mentors and peers, many of whom have been important role models in my decision to pursue medicine and research. I have also learned so much from these experiences that extended beyond technical lab skills to other crucial skills like teamwork, communication, and critical thinking. It’s also incredibly enriching to explore the wide range of research activities, such as attending conferences, mentoring younger students, and receiving professional guidance.

What is one piece of advice you have for other students thinking about getting involved in research?
Find a topic you’re really passionate about, and don’t hesitate to reach out to the researchers in the field. It’s extremely important to be personally invested in the research you’re doing, as it helps you realize why it’s worth spending so much time working to discover novel mechanisms and solutions. It’s not always an easy process, but it’s a valuable experience that will drive you to grow both personally and professionally.

What are your future career goals?
I’m still exploring different career paths, and my current research has been a wonderful opportunity for me to immerse in the intersection between science and medicine. In the future, I would like to continue conducting research to improve quality of life and medical treatments, as well as directly provide these treatments to others.

Jakob von Morgenland

Jakob von Morgenland is a senior majoring in Neuroscience and double minoring in Biomedical Research and Applied Developmental Psychology. He is currently conducting research in Dr. Sharmila Venugopal’s lab, in the department of Integrative Biology and Physiology.

Jakob recently published a first-author paper in the Encyclopedia of Computational Neuroscience titled, “Hill’s Model for Muscle Physiology and Biomechanics.

Read Jakob’s interview with us below:

How did you first get involved in your research project?

My first quarter at UCLA, I took LS30A with Dr. Sharmila Venugopal; I remember during the first lecture, she was discussing her research in neurodegeneration and I was immediately enthralled. Near the end of the quarter, I asked to join Dr. Venugopal’s lab, and I began learning experimental and computational research techniques. However, over the course of my 4 years in the lab, I have taken a much greater focus in conducting computational neuroscience research. My published work is a continuation of a larger study creating an in silico model of a basic neural reflex circuit to investigate how neurodegeneration causes biophysical changes in the properties of neurons and muscles.

How would you describe your research experience at UCLA?

Before coming to UCLA, I did not really have a concept of what scientific research was; in fact, I was planning on attending a university to study musical performance but had to change my career plans due to personal issues. When reevaluating my career options, I found this indescribable interest in neuroscience; I decided to attend UCLA majoring in neuroscience to better explore the field. My primarily computational research experience in Dr. Venugopal’s lab, as well as my clinical research studying schizophrenia in Dr. Yee-Bradbury and Dr. Miller’s lab, have developed my passions and helped guide me towards pursuing an MD/PhD program post-graduation. To put it simply: research at UCLA has been enriching and eye-opening to what matters most to me.

What is one piece of advice you have for other students thinking about getting involved in research?

Before reaching out to potential mentors, do your own individualized research! UCLA offers opportunities to interact with thousands of experts in a vast variety of fields, which may feel overwhelming at first. Ask to meet with mentors whose research most interests you to discuss their research; this is great to see if your interests align with the goals of the research lab, as well as giving you prime interaction time with an expert in their field.

For those who have just started research, do not be intimidated trying to understand everything early on! Ask questions and be proactive in receiving feedback or help about your assignments. Everyone in your lab wants you to grow and become the best scientist you can be, so do not hesitate to lean on them for support.

What are your future career goals?

I want to pursue an MD/PhD to eventually become a physician scientist; as of right now, I am very interested in pediatric neurosurgery to help save children’s lives while working in an intellectually challenging and stimulating field. Additionally, I want to continue my research in motor dysfunction by looking for clinical solutions, primarily in neuroprosthetics and neurobionics. Finally, I would like to pursue teaching at a collegiate level in computational biology and neuroscience to help cultivate passions of young aspiring scientists like myself.

Robert Lamm (2012) featured in Amgen Scholars News Article (2021)

Robert Lamm was featured in the Amgen Scholars News article titled, “From Puzzles and Gadgets to Biotech Startups: Charting a Course for Success.” Bob speaks about his time in the Amgen program in 2012 and how his journey from PhD to Biotech Start-up.

Jingwen Zhou (2015) featured in Amgen Scholars News

Jingwen Zhou and Tatsuya Araki were featured in Amgen Scholar News winter 2021 article titled, “Five Years Later: Romance and Research Bud from Amgen Scholars.” The article describe how the Amgen Program brought Jingwen Zhou and Tatsuya Araki together and enabled them to pursue their career goals.