Understanding the molecular mechanisms of vascular calcification and fibrosis

UCLA PI Name: Xinjiang Cai
E-Mail: xinjiangcai@mednet.ucla.edu
Division/Department: Cardiology/Medicine
Lab website: https://cvbiol.med.ucla.edu/people/xinjiang-cai-md-phd
Expected Weekly Time Commitment: 5-10 hours

Job Description: Our laboratory at the University of California, Los Angeles is a leading research lab dedicated to advancing scientific knowledge in the field of vascular biology. We are seeking a talented and enthusiastic UCLA undergraduate with a primary focus on the molecular biology of vascular calcification. The successful candidate will join our dynamic research team and play an important role in advancing our understanding of the molecular mechanisms underlying vascular calcification.

Per Student Research Program (SRP) program instruction, all student researchers must first receive clearance from the UCLA Health Sciences Volunteer Office.

The responsibilities of this position encompass, but are not confined to, the following:
• Mammalian Cell Culture: cultivation of mammalian cells, including human cells.
• Molecular Techniques: RNA isolation, real-time RT-PCR, SDS-PAGE gels, Western blotting, immunochemistry, histochemistry, ELISA, and enzymatic assays.
After the completion of required animal training, the candidate may contribute to
• Breeding and Injections: Experienced in the setup and maintenance of mouse breeding, injections, and general animal handling.
• Mouse Handling: ear tagging for identification, tail sampling for DNA isolation, weaning of animals, and PCR-based genotyping.
• Sample Handling and Procedures: Competent in mouse euthanasia, tissue harvest (including blood), and histology of animal tissues.

Application Instructions: Please send your application along with a copy of your most up-to-date résumé to Xinjiang Cai, MD PhD via email xinjiangcai@mednet.ucla.edu. We can accommodate 1–2 undergraduate students in the lab, depending on the availability of active projects.