Audrey Fung graduated from the University of California, Irvine with a B.S. in Microbiology & Immunology. During her time as an undergraduate, she worked in the lab of Dr. Weian Zhao studying CAR-T cells and bispecific antibodies. As an Amgen Scholar at UCLA, she is working in the lab of Dr. Lili Yang in the Department of Microbiology, Immunology & Molecular Genetics researching creatine as an energy source for T cells. Tumor-infiltrating T cells play a key role in anticancer immune responses, but the activation and maintenance of those responses are highly energy demanding. Low glucose availability and hypoxic conditions in the tumor microenvironment (TME) induce additional metabolic stress, limiting the T cell anticancer immune response. She is investigating whether creatine supplementation will enhance T cell antitumor activity via the creatine kinase/phosphocreatine/creatine (CK/PCr/Cr) system which uses creatine to store high energy phosphates from ATP to balance the supply and demand for energy in a cell.  She will be using mice implanted with ovarian cancer engineered to express luciferase to characterize the role of creatine supplementation alone or in combination with PD-1/PD-L1 blockade treatment. Audrey would like to thank the Amgen Foundation and Amgen Scholars Program for the opportunity and the Yang Lab at UCLA for their mentorship and support.