STUDENT SPOTLIGHT

Meet Ashlyn Sloane! Ashlyn is a senior majoring in neuroscience and is looking to pursue a PhD in Neuroscience or Human Genetics. She is involved in UCLA’s Amgen Scholars Program, a national program aimed to increase learning and networking opportunities for students committed to pursuing a career in science or engineering. Her current research project explores mTOR signaling defects and the potential rescue of cellular phenotypes by rapamycin of Jordan’s syndrome patient cell lines. When asked about one piece of advice Ashlyn would have for students just getting into research she says, “Don’t be afraid to do research in a field outside of your comfort zone! You might feel like you have to do research in a field that reflects exactly what you want to study for your career, but your undergraduate experience is a perfect time to explore.”

1. How did you first get involved in your research project?

I chose to major in Neuroscience because I am passionate about researching neurodevelopmental disorders, particularly autism. I reached out to Dr. Wells during my sophomore year because I was drawn to his interdisciplinary approach to research and his use of novel techniques, and I feel so lucky that I am a part of such a caring, dedicated team! My current research project explores mTOR signaling defects and the potential rescue of cellular phenotypes by rapamycin of Jordan’s syndrome patient cell lines. Jordan’s syndrome is characterized by autism and macrocephaly, and it has been gratifying to research this disorder. My research aligns closely with the field I want to pursue for my career, which is very motivating!

2. How would you describe your research experience at UCLA?

My research experience at UCLA has been incredibly rewarding and inspiring! I have grown as an undergraduate researcher far more than I could have imagined when I first started college. But more importantly, in both of my undergraduate research experiences, I have found a community of like-minded individuals who are passionate about mentorship and pursuing answers to complex questions. They have helped me grow as a person and have shown me that the research environment can be uplifting and collaborative.

3. What is your year and major?

Senior; Neuroscience

4. What is one piece of advice you have for other students thinking about getting involved in research?

Don’t be afraid to do research in a field outside of your comfort zone! You might feel like you have to do research in a field that reflects exactly what you want to study for your career, but your undergraduate experience is a perfect time to explore. You have an incredible opportunity to learn and grow in a research lab as an undergraduate, so take advantage of this! If you have your heart set on cancer research, but you hear of a cool lab that studies cardiovascular disease, don’t be afraid to pursue that path. Your interests will evolve as you gain more experience, and sometimes, it’s just as important to figure out what you don’t like as it is to figure out what you do like.

5. Have you attended a conference before? If so, can you describe your experience on preparation, presenting, etc.?

I have not attended a conference before, but I have presented with the Amgen Scholars Program about my summer project at the Undergraduate Research Showcase for SPUR Programs! It was a fantastic experience to prepare for an oral presentation. You have to be able to communicate the bigger picture “why” of the research that you’re conducting to people who might not know that much about it. For example, I’m researching a rare neurodevelopmental disorder that affects only a small subset of people worldwide. I didn’t know about the disorder before I started doing research in my lab, so it’s extremely important to convince people to care about what you’re working on when you share an oral presentation.

6. Have you had your work published? Can you talk about what that process was like?

My first graduate student mentor, Ileana Callejas from the lab of Dr. Jennifer Jay, submitted a paper and it’s currently in review! We researched the impacts of antibiotic resistance genes in the LA River Watershed. I will be listed as one of the contributing authors. It was an amazing experience to learn from Ileana during her last year of graduate school, and I was very proud to contribute to such an important and relevant topic.

7. What are your future career goals?

One of my future career goals is to pursue a PhD in Neuroscience or Human Genetics and ultimately study the genetic and molecular origins of neurodevelopmental disorders. I also want to find ways to incorporate more science education and awareness into my research so that people who have personal connections to these neurodevelopmental disorders, but may not have a scientific background, can learn more!

8. Please list any URC/departmental programs you are/were involved in. How has your experience been in AMGEN?

I have also been extraordinarily lucky to expand my research experience at UCLA through the Amgen Scholars Program! This program has been a rewarding and valuable experience that has taught me how to communicate about science, how to stay motivated despite setbacks, and how to navigate the next steps after graduation. It has been very fulfilling to work on my individual project in a focused environment and to dedicate all of my time to troubleshooting, asking scientific questions, and growing my confidence.

9. What was the impact of undergraduate research on your career path?

Undergraduate research has shown me the path I want to take for my career path, and it has shown me that research can be exciting, frustrating, motivating, and challenging. Research is not a linear path, but when you reach your end goal, reflecting upon that twisting, up-and-down path makes the successes that much more rewarding!

10. What are your pronouns?

she/her