University of California, San Diego Junior Biochemistry Faculty Mentor: Dr. Albert Lai Angie Santos is a rising junior at UCSD majoring in biochemistry. There, she conducts research in the Olivier George Lab, an addiction research laboratory, investigating the behavioral and neurological components of addiction via single-cell whole-brain imaging (iDisco+). As part of the UCLA Amgen Scholars program, Angie is in the Albert Lai Lab in the Department of Neurology. The Lai Lab investigates the use of epigenetic editing to improve the effectiveness of chemotherapy against glioblastomas, an aggressive form of primary brain cancer. Glioblastomas have the lowest survival rate compared to other brain tumor types and there’s currently no known cure. Such a poor prognosis emphasizes how necessary it is for the development of possible therapeutics to help treat glioblastoma patients. Angie’s summer project focuses on the validation of a potential gene therapy that could improve glioblastoma patient outcomes. Angie would like to thank Dr. Albert Lai, Blaine Eldred, and the rest of the Lai Lab for their incredible support and mentorship throughout the program. She would also like to thank the Amgen Foundation for making her research experience at UCLA possible.