STUDENT SPOTLIGHT

Meet Lucine Ksajikian! Lucine is a fourth year Psychobiology major who is looking to become a physician specializing  in radiation oncology. She was previously involved in the URC – Sciences Summer Program, 10-week opportunity for UCLA undergraduates to undertake research with a UCLA faculty and receive professional development through workshops and seminars. Lucine is currently an undergraduate researcher in the Laboratory for Image-Guided Immunotherapy, led by Dr. Oluwatayo Ikotun.

1.How did you first get involved in your research project? Tell us a bit about the lab you are in and the research you are conducting.

I am an undergraduate researcher in Dr. Ikotun’s lab, the Laboratory for Image-Guided Immunotherapy, where we focus on developing diagnostic imaging tools to enable in vivo visualization of the cancer immunity cycle and investigating the validity of a single-agent targeted radioimmunotherapy approach to overcome challenges in the effectiveness of current cancer immunotherapies. I first became involved in research through the introductory course of the Biomedical Research Minor, where I participated in Dr. Ikotun’s seminar and developed a strong interest in the fi eld of cancer immunology and radiotheranostics. My current projects specifically focus on integrin-targeted therapies for non-small cell lung cancer, including investigating αvβ6 radioligand therapy for chemotherapy-resistant tumors and evaluating the antibody-drug conjugate sigvotatug vedotin (SGN-B6A), with an emphasis on how these approaches directly eliminate tumor cells, modulate the tumor immune microenvironment, and enhance responsiveness to immunotherapy.

2. How would you describe your research experience at UCLA?

My research experience at UCLA has simply been transformative. Under Dr. Ikotun’s mentorship, I have had the rare opportunity as an undergraduate to engage directly with various advanced assays and develop genuine independence at the bench. Working at the forefront of translational cancer research has allowed me not only to recognize critical gaps in current therapies but also to work in projects that actively work to bridge those gaps: from concept to execution. With that, I am deeply grateful for the privilege of contributing to this eff ort within an institution like UCLA, where unparalleled facilities and resources continually expand the scope and impact of our research.

3. What is your year and major?

I am a 4th year Psychobiology major.

4. What is one piece of advice you have for other students thinking about getting involved in research?

The foundation of research is passion. Pursue opportunities in areas that genuinely spark your curiosity and align with what you hope to contribute, because it is your enthusiasm and commitment that will ultimately drive both your learning and your success as a researcher.

5. What are your future career goals?

My future goal is to become a physician specializing in radiation oncology. Throughout medical school, residency, and my career as a physician, I plan to remain actively engaged in research, with a particular focus on immunology, oncology, and radiotheranostics.

6. Please list any URC/departmental programs you are/were involved in. How has your experience been in these programs?

In Summer 2025, I participated in the URC-Summer Science Program, where I received a stipend to pursue my independent research project under the guidance of my faculty mentor. The program was transformative for my growth as a researcher, supporting my project directly while also providing weekly seminars and workshops led by Dr. Jorge Avila and distinguished researchers from in and out of UCLA. Through these experiences, I not only gained valuable skills in becoming a better scientist but it also deepened my passion for research and broadened my vision of the possibilities for continuing my work beyond undergrad.

7. What was the impact of undergraduate research on your career path?

My work in translational research has shaped how I view my future career, not as a physician who does research on the side, but as someone whose medical practice and scientific inquiry are inseparably linked. Experiencing firsthand how our research can impact patient outcomes has reinforced my commitment to continue pursuing research throughout my medical journey, contributing meaningfully to both the advancement of science and the delivery of patient care.